module, very first mobile traces are split into responsive and non-responsive determined by the RS with the queried compound and then, if Each and every group contains a minimum of a few samples, the transcriptional profiles of responsive and non-responsive cell lines is often analyzed working with both SAM (Importance Investigation of Microarray; (19)) or possibly a t
To discover putative mechanisms of drug resistance in cancers with BRAF mutations, we very first recognized medicines Energetic in cancer mobile lines with BRAF missense mutations utilizing the from gene to drug
Dysregulated DnaB unwinding induces replisome decoupling and daughter strand gaps that happen to be countered by RecA polymerization PHF2 regulates genome topology and DNA replication in neural stem cells by using cohesin LowTempGAL: a really responsive small temperature-inducible GAL
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